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Scuba Forum / UK Scuba / October 2007

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anti-malaria medication

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floren - 05 Sep 2007 18:44 GMT
Lariam.
This medication is used to treat and prevent malaria.

http://www.canadianmedsworld.com/item.php?id=768&aid=1855
Ian Blakeley - 05 Sep 2007 22:15 GMT
>Lariam.
>This medication is used to treat and prevent malaria.

causes severe depression, anxiety, paranoia, nightmares, insomnia,
seizures, peripheral motor-sensory neuropathy, vestibular (balance)
damage and central nervous system problems.

Not really ideal for a diver

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Ian

Ken - 05 Sep 2007 23:25 GMT
>>Lariam.
>>This medication is used to treat and prevent malaria.
[quoted text clipped - 4 lines]
>
> Not really ideal for a diver

Might I suggest that neither is malaria? Or for anyone else for that matter.
Just because a drug has a recognised side effect doesn't mean you will
certainly experience it.

Ken
Jason - 07 Sep 2007 17:04 GMT

> Might I suggest that neither is malaria? Or for anyone else for that
> matter. Just because a drug has a recognised side effect doesn't mean you
> will certainly experience it.

Lariam is particularly bad for divers as it can mask symptoms of DCS. I
usually got with Malarone. It's expensive but you don't have to take it
weeks before and afterwards.

Jason

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See http://www.scuba-addict.co.uk/ for UK diving reports and the UK
Underwater Visibility Database. View the database or add your own report

Ken - 07 Sep 2007 23:18 GMT
>> Might I suggest that neither is malaria? Or for anyone else for that
>> matter. Just because a drug has a recognised side effect doesn't mean you
[quoted text clipped - 3 lines]
> usually got with Malarone. It's expensive but you don't have to take it
> weeks before and afterwards.

That's as may be, and I agree as it happens - in broad terms. Might I
suggest an alternative strategy? Various strains of malaria are variously
sensitive or resistant across the spectrum of antimalarials. You and I and
everyone else have little choice as to what is the preferred prophylactic
antimalarial to take when visiting any given part of the malaria-affected
world. So, if there is a particular medication which it is wiser not to
take, or one prefers not to take for whatever reason, avoid going to those
places where that anti-malarial is the drug of choice.

It's one of a number of choices to be made. I for one would prefer not to go
to a country where my personal safety is at great risk, nor would I go where
my health is at great risk either. However I would not dream of stopping
anyone from going to places I personally would rather avoid.

Ken
Jason - 09 Sep 2007 20:49 GMT
> That's as may be, and I agree as it happens - in broad terms. Might I
> suggest an alternative strategy? Various strains of malaria are variously
[quoted text clipped - 4 lines]
> take, or one prefers not to take for whatever reason, avoid going to those
> places where that anti-malarial is the drug of choice.

Ken, have you ever been anywhere where they said you needed lariam? As far
as I am aware, there is always a choice. And in the areas with the most
resistant strains, it comes down to lariam, doxycycline or malarone.
There's not much to choose in terms of effectiveness between any of them,
but some people react badly to some drugs and not others. The medical
advice I was given was to find one of the 3 that you didn't have a
reaction to, and stick with it.

> It's one of a number of choices to be made. I for one would prefer not to
> go to a country where my personal safety is at great risk, nor would I go
> where my health is at great risk either. However I would not dream of
> stopping anyone from going to places I personally would rather avoid.

Hell, you might get hit by a bus tomorrow.

Jason

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Ken - 10 Sep 2007 18:22 GMT
>> That's as may be, and I agree as it happens - in broad terms. Might I
>> suggest an alternative strategy? Various strains of malaria are variously
[quoted text clipped - 14 lines]
> advice I was given was to find one of the 3 that you didn't have a
> reaction to, and stick with it.

. . . . as long as it's a drug to which the malaria in the region you are
visiting is not resistant.

>> It's one of a number of choices to be made. I for one would prefer not to
>> go to a country where my personal safety is at great risk, nor would I go
>> where my health is at great risk either. However I would not dream of
>> stopping anyone from going to places I personally would rather avoid.
>
> Hell, you might get hit by a bus tomorrow.

Indeed I might - but I might not. It may be an asteroid falling from the sky
instead. It's a question of minimising / managing / accepting risk (or not)
and in what context.

Ken
Mick Whittingham - 12 Sep 2007 09:13 GMT
> . . . . as long as it's a drug to which the malaria in the region you are
>visiting is not resistant.
[quoted text clipped - 5 lines]
>>
>> Hell, you might get hit by a bus tomorrow.

You may not have to leave the UK.

http://lifeandhealth.guardian.co.uk/health/story/0,,2167212,00.html
Signature

Mick Whittingham
'and I will make it a felony to drink small beer.'
William Shakespeare, Henry VI part 2.

Ken - 12 Sep 2007 13:40 GMT
>> . . . . as long as it's a drug to which the malaria in the region you are
>>visiting is not resistant.
[quoted text clipped - 9 lines]
>
> You may not have to leave the UK.

Indeed, even before this, it was a rare but refcognised occurrance to
contract malaria in the UK if you lived a short distance from an airport
which had flights coming in from places which did have it. All it takes is
ONE mozzie bite, and you're it!

Ken
Keith Manning - 13 Sep 2007 19:52 GMT
> Indeed, even before this, it was a rare but refcognised occurrance to
> contract malaria in the UK if you lived a short distance from an airport
> which had flights coming in from places which did have it. All it takes is
> ONE mozzie bite, and you're it!
>
> Ken

This is my thoughts on the plane on the way back from Bonaire. Bonaire is
supposedly not a malaria hotspot, but Ecuador is and we all jump on a plane
that has just landed from Ecuador on the way home.

Keith
Gordon Henderson - 10 Sep 2007 10:27 GMT
>> Might I suggest that neither is malaria? Or for anyone else for that
>> matter. Just because a drug has a recognised side effect doesn't mean you
[quoted text clipped - 3 lines]
>usually got with Malarone. It's expensive but you don't have to take it
>weeks before and afterwards.

I'm just back from 2 weeks in the Solomons. I took (and am still taking)
what was recomended for that area; Doxycycline.

http://www.fitfortravel.scot.nhs.uk/

I think one other in the group took Malarone, but most were on Doxy.

Gordon
Mick Whittingham - 10 Sep 2007 11:31 GMT
>>> Might I suggest that neither is malaria? Or for anyone else for that
>>> matter. Just because a drug has a recognised side effect doesn't mean you
[quoted text clipped - 10 lines]
>
>I think one other in the group took Malarone, but most were on Doxy.

Diving and work has taken me often into several malaria high risk areas.
Notable Kourou in French Guyana.

The recommendation for Kourou from the medical establishment in the UK
was mefloquine weekly and daily chloroquine.

If you are out there for any length of time or familiar with the
environment the French recommended you didn't take anything for malaria
but were very aware of the symptoms. 'IF' you detected any you went
straight to the hospital were checked and if positive bombarded with the
relevant anti malaria drugs. Work meant we were very close to good
medical facilities.

Taking mefloquine had the effect of masking the symptoms of one type of
malaria out there and that could have been fatal. It was for one
colleague.
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Mick Whittingham
'and I will make it a felony to drink small beer.'
William Shakespeare, Henry VI part 2.

Jason - 10 Sep 2007 19:59 GMT

> I'm just back from 2 weeks in the Solomons. I took (and am still taking)
> what was recomended for that area; Doxycycline.
>
> http://www.fitfortravel.scot.nhs.uk/
>
> I think one other in the group took Malarone, but most were on Doxy.

It does list malarone and lariam as alternatives on that page though by
their generic names. The big advantage with malarone is that you only take
it 2 days before and one week after. It's a lot longer for doxy, isn't it?

So have you got a pink nose?

How was the diving? Who did you dive with? What sort of depths?

Jason

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Gordon Henderson - 10 Sep 2007 21:00 GMT
>> I'm just back from 2 weeks in the Solomons. I took (and am still taking)
>> what was recomended for that area; Doxycycline.
[quoted text clipped - 6 lines]
>their generic names. The big advantage with malarone is that you only take
>it 2 days before and one week after. It's a lot longer for doxy, isn't it?

2 days before and 4 weeks after. I can live with that..

>So have you got a pink nose?

No. It rained every day. I didn't even use sunblock which, as those who
know me, know I really need as I can get sunburnt on a boat in January
in the UK ...

>How was the diving? Who did you dive with? What sort of depths?

Dived with Tulagi Dive. We were doing 2 55-70m dives each day. I was
spending from 30 to 45 miuntes on the bottom for a total run-time of 1.5
to 2 hours give or take.

 http://www.tulagidive.com.sb/Index1.htm

We did 13 dives in total. It should have been nearer 20, but the local
airline is rubbish.

Getting there (& back!) was the biggest headache. We flew the wrong way
round - Heathrow -> LA -> NZ -> Brisbane where we then had the luxury of
one night in a hotel, then onto the Solomons. Or so we thought... They
cancelled the flight on us because they couldn't pay the fuel bill.
(or something). We flew the next day, but lost another day's diving as
they had to land in Cairns to get fuel so by the time we got there,
we couldn't make the sea crossing (1.5 hours in the dive boat) as it
was dark.

The dives were: USS Aaron Ward (x4), Kanawah (x4), RNZN Moa, USS John
Penn, Tama Maru, Azumasan Maru and the reef. (Some did the bow of the
USS Minneapolis too)

Weather wasn't kind to us either - it rained every day, making the
visibility poor - I've had clearer 70m dives in the UK! The island had
variable power - so some days there was no running water or lights.
Fortunately the dive centre had their own generator, so could still run
the compressors.

So it was a good trip, but the logistics of getting rebreathers out there,
arranging sofnolime & helium were "challenging"...

Gordon
Jason - 10 Sep 2007 21:16 GMT
> No. It rained every day. I didn't even use sunblock which, as those who
> know me, know I really need as I can get sunburnt on a boat in January in
> the UK ...

And sun sensitivity is a side effect of doxy.

> So it was a good trip, but the logistics of getting rebreathers out there,
> arranging sofnolime & helium were "challenging"...

Yeah, I can imagine. I looked at going there once and decided to go to
Vanuatu as it seemed a bit easier. Even there, where they've been diving
regularly for much longer, getting a pair of fins that were any good was a
struggle let along exotic luxuries like helium.

Jason

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See http://www.scuba-addict.co.uk/ for UK diving reports and the UK
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Brad - 11 Sep 2007 01:48 GMT
>> No. It rained every day. I didn't even use sunblock which, as those who
>> know me, know I really need as I can get sunburnt on a boat in January in
[quoted text clipped - 12 lines]
>
> Jason

When doing dives in the pacific islands you could try contacting Bob at the
Lae BOC Gas centre in PNG. He is the manager for the pacific islands and
could arrange things or give advice on what is available. He is a diver and
his daughter an instructor so he could be sympathetic to divers. I had my
first dive with Bob and it was interesting to say the least.
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Brad Leyden
6° 43.5816' S 146° 59.3097' E  WGS84
Forecast for tomorrow, heavy showers overnight with a fine day.
Temps: min 24ºC max 32ºC
Bet I'm right for where I am, Could you say the same without changing it
daily?
To mail spam is really hot but please reply to thread so all may benefit (or
laugh at my mistakes)

Jason - 05 Sep 2007 23:31 GMT
> causes severe depression, anxiety, paranoia, nightmares, insomnia,
> seizures, peripheral motor-sensory neuropathy, vestibular (balance) damage
> and central nervous system problems.
>
> Not really ideal for a diver

Yeah it takes a special sort of f*ckwit to spam the one anti-malarial not
recommended for divers to uk.rec.scuba.

Jason

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See http://www.scuba-addict.co.uk/ for UK diving reports and the UK
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ZenDiver - 05 Sep 2007 23:44 GMT
>> causes severe depression, anxiety, paranoia, nightmares, insomnia,
>> seizures, peripheral motor-sensory neuropathy, vestibular (balance) damage
[quoted text clipped - 6 lines]
>
> Jason

Although my experience of Lariam was quite good.  In 2000 I spent about
6 weeks on a fairly-drug-resistant-malaria-ridden island in the
Philippines.  I was taking Lariam for the duration, most others were on
Doxy.  I didn't have any 'bad' side effects, but I did have some wicked
dreams.

jon
Brad - 06 Sep 2007 04:19 GMT
There are new treatments available and it is worth going on one at least 6
weeks before so you can judge the results. some make you sick for the day
you take them others make you hypersensitive to the sun. For a short time
visit to a malaria are they are worthwhile long term not so much as the
treatments stuff you as much as the malaria does. None of the long term
expats here that I know of take preventive meds but all will take the
treatments with them whenever they travel as that is usually when the
malaria will strike.
Take simple steps to avoid the mozzies,
1. Try to stay elevated around dusk and dawn, at least 3 feet above the
ground reduces the risk greatly.
2. If you can stand a mozzie net, use that while sleeping (preferably a
treated net) and if that is too hot use coils or a citronella based oil
(when available) in a lantern.
3. Cover up when you can, especially the legs.

Some people get bad symptoms from malaria and in others it seems like a head
cold. If you start getting bad migraine headaches head to a quack ASAP as
the cerebral strain is deadly and hours can count. For the other 2 common
types it's just uncomfortable if you are healthy. In Malaria prone areas the
treatments are cheap to buy and as I have said before if you don't use them
you can donate them as you leave. Disposable test kits are available for
less than £5 and give a result in 5 minutes, even if you take the
preventative they can be a handy backup. Everyone I know gets malaria, it's
just a part of life, I'm overdue at the moment so perhaps I shouldn't have
said anything.

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Brad Leyden
6° 43.5816' S 146° 59.3097' E  WGS84
Looking at Steven Hawkings' "String Theory"
All matter in the universe is composed of tiny vibrating strings
So all things are made from music.
Music to my ears is my Tiagra 50W screaming when towing a Wombat from
Pakula.
That must be why nothing else in the universe matters except fishing.
To mail spam is really hot but please reply to thread so all may benefit (or
laugh at my mistakes)

>
>>> causes severe depression, anxiety, paranoia, nightmares, insomnia,
[quoted text clipped - 15 lines]
>
> jon
tim.griezitis@gmail.com - 17 Sep 2007 15:04 GMT
> Lariam.
> This medication is used to treat and prevent malaria.
>
> http://www.canadianmedsworld.com/item.php?id=768&aid=1855

Hope you don't mind the interjection, but I used "Malarone" when I
went to Sipadan Island (off Borneo) last year which doesn't have the
side effects Lariam has (I know I tried Lariam in Africa and I had
biting headaches and nose bleeds which I've never expereinced since a
small child). I did have a few nightmares on Malarone but ask the DAN
help line if you;re not sure or a good hyperbaric dive doctor (DDRC
can help if you want good advice). As with all medicines and diving
ask a diving doctor who can get access to your medical records.

One benefit is you only need to start taking the tablets (just 1 a
day) the day before arriving in the mosquito infested country you;re
diving in and 1 extra tablet the day you get back (or out of the
infected area to be more accurate). They're not cheap though, so shop
around (boots online, or I got mine from Tescos !).

Tim
Dan Logan - 15 Oct 2007 11:00 GMT
On Sep 18, 3:04 am, "tim.griezi...@gmail.com"
<tim.griezi...@gmail.com> wrote:

> > Lariam.
> > This medication is used to treat and prevent malaria.
[quoted text clipped - 17 lines]
>
> Tim

Bit late to the discussion, but I was a diver and medic in a nice
malaria infested location for a while, and the three recommended anti-
malarials were doxycycline, mefloquine and malarone...

I was on mefloquine for a year, because I don't get any of the side
effects, but I did see a few people have nightmares and/or
hallucinations (in one case a girl kicked her boyfriend off a bed
because she thought he was covered in spiders).

Doxy was the drug of choice due to cheapness and lack of perceived
signs from issuing doctors in the UK, but I would say that I saw at
least a 1 in 5 rate of photosensitivity with the worst examples
requiring people to wear 40+ SPF, gloves and a hat due to severe
burns, peeling skin and so on... mostly it was cases of pink nose and
fingers though...

Malarone has not really had the same level of testing as the others,
but it seems to be the best in terms of adverse effects although it is
the most expensive.

Dan.
 
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